D-Chiro-Inositol

D-chiro-inositol is a complementary form of inositol that plays a specialized role in insulin signaling within the ovaries and other tissues, comprising only about 5% of the body's natural inositol content. While myo-inositol supports follicle development and egg quality, D-chiro-inositol assists with glycogen synthesis and androgen production regulation in the ovaries. Research suggests that women with PCOS benefit most from D-chiro-inositol when it's taken alongside myo-inositol in the body's natural 40:1 ratio, rather than in high doses on its own—as excessive D-chiro-inositol may actually impair egg quality.